Category: science

A Little Prick

A Little Prick

Sometimes I fret that I spend too much time on the fence, but immunisation is a no brainer. The science is sound and it turns out that a little prick can do even more than prevent terrible disease.

New Scientist Magazine reports that a recent study into the side effects of vaccines have had a “wider ranging influence on our immune systems than we ever imagined.”

A study undertaken by Danish Professor Peter Aaby and colleagues in Africa has shown that measles vaccination also reduces death in all other infections by a third by reducing the instance of pneumonia and diarrhoea. The vaccine teaches the body how to combat other infections.

peter aaby measles immunisation
Peter Aaby with Manuel Fernandes

In the west there is evidence to suggest that some vaccines help reduce the effects of eczema and asthma. These unexpected bonuses are known as “non-specific effects”.

Scientists have been noticing these non-specific effects since the early 20th century but no one has taken much notice until Peter Aaby’s work in the West African state of Guinea-Bisseau.

If you are on the fence about immunisation, follow the science. Use Google Scholar and read the meta studies. The Australian government website, Immunise Australia has some useful information as well. Follow the link to New Scientist for more detail.

immunise tshirt

Young Blood

Young Blood

It’s been a while between drinks (strictly figuratively speaking). Speaking of which I have been favouring a lovely pinot noir discovered with a sensible friend in a seaside cafe during a wild storm that nearly knocked us into the Indian Ocean.

Two Paddocks Picnic Pinot Noir is a from actor Sam Neill’s vineyard in Central Otago in the south of New Zealand.

sam neill two paddocks

I know little of wine but I could keep drinking this one until the Central Otago cows come home.

On another type of red, it was reported this week in New Scientist that there’s some blood-swapping going on. For some years researchers have been seeing what happens when the blood of young mice gets put into old mice with interesting results which hit the press this May, enough to spawn a human experiment to happen in October. Alzheimer’s patients will be given transfusions of blood from healthy young people with an eye to reversing some of the damage caused by this terrible disease.

If successful the procedure has widespread ramifications. In a Flowers for Algernon twist it may only work for a short time, perhaps a day, but as the article points out even a day of greater health will warrant further research.

blood

While the first thought of many my age will be the endless cosmetic applications, there are some genuinely useful rejuvenating effects that could be possible if the trials are successful: New Scientist’s Helen Thomson reports that young blood could help stop or reduce the muscle wastage that occurs with chemotherapy. There is also investigation into the possibility that it could inhibit the growth of tumours.

Perhaps Eric Northman’s healing powers are seated in more than just racy tv drama.

Eric Alexander Skarsgard
Entirely gratuitous photo of Alexander Skarsgard aka Eric Northman

 

Oxygenetix Rules

Oxygenetix Rules

Maths is Fun.

First of all, it’s actually not.

Secondly, I am nervous that my companion to getting through Chapter One of Statistics For Psychologists is a children’s interactive website called Maths is Fun.

Who knew that when you multiply a negative number with another negative number you get a positive number? That’s just plain crazy! Or that when you add things you have to add what’s in brackets before you add and you have to multiply before you add or subtract. Really? Why?

There’s even a song about it. Not as good as the latest Busta Rhymes song, Thank You if you like a bit of hip hop.

Finding a new foundation that acts as a poly filler while looking light and translucent on the skin…now that is fun.

oxygenetix

Say hello to Oxygenetix, introduced to me by a dewy-skinned sensible friend: It was designed by a Beverly Hills makeup artist for a plastic surgeon to cover and even heal procedural scars.

Designed for doctors, Breathable foundation covers and treats a wide variety of skin problems: skin injuries, wounds, rashes, cracked, dry skin, acne scars, rosacea and other skin conditions. On post-surgical scars, patients are re-assured and impressed that after care includes safely camouflaging any evidence of surgery.

Basically, this is a healing cream that also just happens to be a banging good foundation. It comes in a variety of shades so you look like you. I use Beige which seems to be the most popular colour.  It also has an SPF 25 – ticking all the boxes.

It’s a small pump bottle and costs $85 here. I was recently in Beverly Hills (I know, I know…did a little damage in Melrose Ave…) and checked it out there thinking I would stock up cheaply, but in fact their price control is pretty standard so no need to hunt around  for hours online or travel to the States for it as I did. Do let me know if you find differently.

Also it lasts for ages and ages as you use a tiny amount for amazing coverage. I’ve had mine for months, use it religiously and there’s still plenty left.

I bought mine in Subiaco, Perth at Skin Evolution, conveniently located next to Jean-Claude Patisserie in Rockeby Road.

There’s nothing in this shameless promo for me, I still pay the $85 like everyone. Also, they are not likely to give free stuff to someone who has six followers on their blog, are they?

Now if someone could just explain interval ratio scales to me I will be content for the rest of the day.

 

Let’s Do Coffee

Let’s Do Coffee

Finally. Proof from my favourite people (scientists) that coffee is good for you.

Huffington Post reported earlier this week that drinking coffee can lower your risk of developing Type 2 Diabetes. I went to Google Scholar to check the paper the news came from and yes, it’s true.

black coffee

That’s not all my fellow Cimba’s regulars: Coffee has also been discovered to do the following. I am keeping this very short as I know you want to skim over this and rush to the kettle to get cracking.

  • Coffee can lower the risk of developing Parkinson’s by as much as 25%
  • It can help ward off basal cell carcinoma (more so for women than men)
  • It can reduce the risk of developing prostate cancer in men
  • It can reduce the risk of Alzheimer’s by boosting GCSF levels in the brain (google it)
  • It can lower the risk of depression in women by 15% to 20%
  • Finally it can help you spot grammatical (although not spelling) errors in your writing

The ‘dose’ seems to be around three to four cups a day and it’s still unclear as to whether the benefits are specifically tied to the caffeine although the evidence seems to point in that direction.

If this isn’t the best news you’ve had all day…you just haven’t had enough coffee.

So this chick walks into a university…

So this chick walks into a university…

So I enrolled at university yesterday. As a result, I’m feeling hip and cool enough to start all my sentences with “so”.

So I walk in to Winthrop Hall at the University of Western Australia and I want to say I was transported back to my first year of university in the mid-1980s but in fact I felt like someone’s mum (well I guess I am; my oldest is freaking the fuck out at the prospect of possibly sharing a campus with me next year and to be honest I don’t blame her).

So there’s me and all the other (extremely young) students-to-be, sitting in chairs waiting to be taken through Step One (of eight!) of enrollment  playing with our iPads. I was cruising the ‘Net, checking out the holiday snaps of someone I barely know on Facebook as you do but the young people were getting frustrated; couldn’t get online with the free UWA wi-fi link. One guy asked me “So how did you get into the free wi-fi?” “What? Oh, I’ve got 3G…sorry”, I replied. Poor darlings: No working wi-fi, no 3G. They had to just sit there like something out of 1985.

So there I was: Old….but rich. Rich enough to have an iPad with 3G. I was living the dream.

So I get to the front of the queue. By this stage I am in about Stage Three or Four of enrollment.  Each stage took us to a different part of the campus. I even got to see inside the Maths Building. A flushed-with-the-beauty-of-youth girl rushed up to me with handfuls of flyers, handing me each one with a little spiel. At one point she started to hand one to me and then hesitated, looking confused/embarrassed. “Are you a mature-aged student?” she asked. It was like asking someone if they are pregnant as you watch the head crown out of the mother’s body. “Ahh yes, I think I might be!” I said brightly.

[I’m over the So. So is so ten minutes ago.]

A little later, perhaps it was around Stage Six of the enrollment process – they are all blurred now – a handsome young fellow thrust a flyer at me and asked me if I was familiar with the Uni Guild, “you know,” he said, “sundowners and stuff?” From [alcohol-damaged] memory, that was the part of uni back in the day that involved an enormous amount of drinking and staying up late. The sweet chap had obviously been instructed to offer this social opportunity to everyone so I tried to make his day a little easier saying “Yeah I was familiar with it about 30 years ago” Did I want the flyer? “Ahh no that’s okay.” Really? Really.

Stage Seven saw me handing over my now-renewed student card for ID to the computer girl and I got this reaction:

“WHOA! Your student number starts with a ONE! Ohmygod, I have seriously never seen that before. A one…wow! When were you here? Woah!”

But I am saving the best for last and possibly only other Western Australians will truly appreciate this.

Exhausted and nearly brain-dead after going through all those stages of enrollment, I stopped by the university cafe for caffeine. Friends, I paid $1.90 for a coffee. Granted it was a little dampened by the fact I had to show ID (for the opposite reason one usually breaks out ID), but I grinned all the way to the car with my ONE DOLLAR AND NINETY CENT coffee. Best coffee I have ever tasted. I’ll try to sneak a few of you in, maybe we can get some fake ID’s made up…

psychology text book

Heal Thyself

Heal Thyself

This post is about cancer, so first let’s make some jokes about superfoods. That works, doesn’t it?

zucchini pasta

I read a very funny article by Maggie Kelly yesterday. Her view of the clean eating mega-trend that is sweeping the first world. Among the gems, this:

Zucchini pasta is nothing like the real thing. It is like how those people in Argentina were selling rats on steroids as toy poodles. Just not the same.

The photo above is some zucchini ‘pasta’ I once made and thought about blogging. True.

And this.

To some of the more hard-core Clean Eaters telling them that I eat bread is like admitting I masturbate to old Adam Sandler movies whilst listening to One Direction and eating Skittle sandwiches. For them it’s weird, confusing and disturbing.

Before you think I am poking fun at you, disclaimer: I am riding that bandwagon myself. I have a kitchen full of chia seeds and gogi berries. My kids drink the occasional green smoothie – hell, there’s a huge bunch of kale sitting on the bench right this minute – and coconut products are spilling out of the fridge and pantry. It’s a superfood mecca here. I draw the line at pressing my own turmeric capsules but I have friends who do.

What the fantastic and yet slightly annoying trend indicates is a desire for we, the fat, unfit, unhealthy Western World to take our health into our own hands and work on healing. Work on creating and maintaining wellness rather than just fixing sickness. It’s good.

Scientists have been working through this stuff for years. They humbly lean over petri dishes and microscopes occasionally popping their heads up to say “ahh you might want to have a look at this” and bang, there’s a cure for polio or measles or cholera. Now the big strides are being made in the field of cancer research. They are just the coolest people.

I will try to explain cancer and some new research; the idea itself isn’t new but the progress being made is and it’s pretty amazing. Bear with me as I was born without science genes; I am just a science junkie with no insider knowledge.

New Scientist magazine reports that we are finally getting a leg up on finding a way to beat cancer, in this case melanoma, common here in Australia. This new approach has not only made the cells retreat, in some people they have disappeared altogether, within days and weeks in some cases. All thanks to the scientists teaching the good healing cells how to do their stuff.

In order to explain how the new treatment (still in the testing stages) works I have to first semi-plagiarise NS in order to explain how this cancer operates.

Cancer cells are good at hiding. What makes them so scary is they hide in plain sight. You can sometimes see a tumour growing right there on a body and that body’s own immune system simply can’t detect it.

The T cell is the antibody whose job it is to locate and destroy bad cells. The cancer cell grows a surface molecule called a ligand, like a little tentacle that can stick on to stuff. The ligand then binds on to the T cell (the good guy).

Once it has attached to the T cell, it instantly activates a receptor in the T cell called PD-1. You can guess the rest: Once PD-1 is activated, the ligand, along with its sneaky cancer cell becomes invisible to the good guys, the T cells. Tumours are now seen by the body as normal tissue.

cancer cell

Traditionally, cancer treatments have involved trying to kill off cancer cells, however this means killing a lot of good cells too, which is why some cancer patients become even sicker during treatment.

Scientists have worked out how to wake up these T cells. There are three antibodies that are being trialled. Two, Lambrolizumab and Nivolumab work on the PD-1 receptor and the third works on the cancer cell ligand. In each of the therapies, cancer disappeared altogether in nine of those on the trials (135 in one trial and 53 in another) and halved or more in another 75.

“Many effects happened very quickly, sometimes within three weeks,” says Jedd Wolchok of the Memorial-Sloan Kettering Cancer Center in New York, who led the trial.

Jedd Wolchok

Wolchok says that what makes the antibody therapies so exciting is that unlike conventional cancer treatments, such as radio and chemotherapy, they work by reviving the power of the patient’s own immune system – something that has evolved to efficiently dispose of infectious, foreign or abnormal tissue. “They treat the patient, not the tumour,” he says. – New Scientist

All three drugs are now the subject of larger trials involving people with skin, kidney, lung and brain cancers. The third antibody trialled has already shown promising results with early trials of kidney and lung cancer.

So in a nutshell, scientists are working out how to get the body to heal itself from cancer, simply by being able to see the cancerous cells and then just do what it is already really good at. Healing itself. It’s exciting stuff.

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